The company will contribute AI-enabled EDA, simulation and digital twin technologies to support national laboratory research in semiconductors, quantum systems and energy efficiency.
Cadence announced it has joined the Genesis Mission Consortium, the U.S. Department of Energy (DOE) public-private partnership using artificial intelligence (AI) to accelerate scientific discovery, strengthen national security and advance energy innovation. Cadence will contribute AI-enabled design and simulation technology and technical expertise to collaborate with DOE National Laboratories to support Genesis Mission priorities in advanced microelectronics, quantum and superconducting systems, data center energy efficiency and AI-driven scientific workflows.
The Genesis Mission Consortium, launched by Executive Order in November 2025 and led by DOE Under Secretary for Science Dr. Darío Gil, aims to double the productivity and impact of American science and engineering within a decade by connecting the nation’s leading supercomputers, AI systems, experimental facilities and unique datasets across the 17 DOE National Laboratories.
Building on existing Cadence–National Laboratory collaborations
Cadence’s Genesis Mission engagement builds on longstanding collaborations with DOE and DOE/NNSA National Laboratories, including Sandia National Laboratories, Fermi National Accelerator Laboratory, Oak Ridge National Laboratory, Lawrence Livermore National Laboratory, NASA Ames Research Center, Argonne National Laboratory and Brookhaven National Laboratory. Cadence® AI-enabled technologies support modeling, simulation, verification and large-scale engineering analysis aligned with DOE science, energy and national security priorities.
The Genesis Mission Consortium brings together DOE, National Laboratories, other federal agencies, industry and academia to address national science and technology challenges in advanced manufacturing, biotechnology, materials science, nuclear energy, quantum information science and semiconductors.
Cadence’s participation advances its strategy of combining agentic AI, physics-based simulation, digital twin technology and high-performance computing (HPC) to accelerate innovation across semiconductor design, physical AI systems and AI factories. Cadence aims to extend these capabilities to the DOE research community and plans to support Genesis Mission priorities through:
- Subject-matter expertise – Participation in scoping and piloting AI model development and validation, data standards and HPC
- Targeted access to Cadence capabilities – Providing AI-enabled electronic design automation (EDA), system design and analysis (SDA), multiphysics simulation, digital twin, advanced packaging and 3D-IC workflows for pilots and demonstrations
- Workflow integration – Supporting the integration of Cadence workflows with DOE laboratory HPC environments, including reproducible packaging and “AI performance” benchmarking
- Workforce development – Collaborating with National Laboratories and academic partners on training and curriculum for AI-enabled engineering
For more information, visit cadence.com.
