to transform AI-driven silicon, systems and drug design.
At its annual CadenceLIVE Silicon Valley 2025 event, Cadence announced an expansion of its Cadence Millennium Enterprise Platform with the introduction of the Millennium M2000 Supercomputer, featuring NVIDIA Blackwell systems. This system offers AI-accelerated simulation for enhanced speed and scale across engineering and drug design workloads.
The new supercomputer integrates Cadence’s industry-leading solvers with NVIDIA HGX B200 systems, NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs and NVIDIA CUDA-X libraries and solver software. This combination reduces simulation run times and offers up to 80X higher performance compared to CPU-based systems for electronic design automation (EDA), system design and analysis (SDA), and drug discovery applications. The supercomputer features a co-optimized hardware-software stack that improves performance while reducing power consumption by up to 20X across various fields, supporting AI infrastructure development, physical AI machine design, and drug design advancements.
The next generation of AI for infrastructure, physical AI, and sciences requires advanced computational power in data centers and edge devices. Building on the success of the Millennium M1 Supercomputer, known for its performance and energy efficiency in computational fluid dynamics (CFD) simulations, the Millennium M2000 Supercomputer utilizes Cadence’s suite of EDA, SDA, and molecular software solvers to perform large-scale simulations that were previously difficult to achieve. This technology is transforming approaches to semiconductor and 3D-IC design, data center digital twins, drug discovery modeling, and other engineering challenges in markets such as hyperscale computing, automotive, data centers, and aerospace and defense.
Advancing semiconductors and 3D-IC design
The industry’s first purpose-built emulator for AI design, the Millennium M2000 Supercomputer combines all the multiphysics capabilities needed to analyze and optimize 3D-IC and advanced packaging designs, including power, thermal, stress/warpage and electromagnetics. This enables superior quality in a fraction of the time, ensuring engineering teams can achieve greater reliability and efficiency in their product development cycles. For example, traditional semiconductor chip-level power integrity simulations are limited to small windows of time. Customers can now deliver simulations in less than a day with one Millennium M2000 Supercomputer that previously would have taken hundreds of CPUs almost two weeks.
Accelerating autonomous system design
The AI infrastructure buildout requires a significant investment in data centers and compute infrastructure. Doing this in an energy- and resource-efficient manner is critical to delivering the next generation of foundation models from AI factories. Digital twins improve operational efficiencies, reduce risk and lower total power consumption. The Millennium M2000 Supercomputer accelerates the design and operation of these data center digital twins and the modeling process required for the racks, boards and equipment that power them.
The Millennium M2000 Supercomputer also enables high-accuracy and high-capacity virtual simulations of machines that will embody AI outside of data centers, such as autonomous transportation, drones and robotics. To design these systems effectively, the combination of accelerated compute and computational software unlocks improved designs in a shorter time by delivering virtual wind tunnels that can precisely simulate real-world conditions. Designers of electronic and mechatronic systems can now make crucial decisions in less than a day versus multiple days, saving both time and energy compared to using a CPU-based Top 500 supercomputer cluster with hundreds of thousands of processors.
Advancing life science innovation
Cadence Molecular Sciences accelerates drug discovery by enabling pharmaceutical customers to perform more simulations in less time with the Millennium M2000 Supercomputer. Cadence’s Orion® Molecular Design Platform on Cadence OnCloud, available on the Millennium M2000 Supercomputer, equips researchers with unmatched computational power to speed up the discovery of potential drug candidates and enhance process scalability. As a result, customers can explore more design scenarios and iterations within tighter deadlines, leading to faster innovation and improved product development.
Availability
The Millennium M2000 Supercomputer is available both in the cloud and as an on-premises appliance.
For more information, visit cadence.com.
